As promised by IceFrog, he'll answer a few question regarding Dota 2 in due course and that time is now! Quite a large number of question were answered including reconnection issues, replay seeking, regional support and hardware requirements. One of the biggest revelation is beta testing. The frog promises we will be able to test the game before the release date in the future.

Q: Is there reconnect support for DotA 2? (by Vanes-UT)
A: This was actually one of the very first things we added early on, before the game was stable, in order to help with testing. You’ll also be able to have a friend of similar skill level substitute for you in case you have to leave. Players that want to improve their reputation in the game and community will also be able to help out by joining ongoing games that are missing players.


Q: Can I still play with my friends from America even though I am European? (by Adam Mosley)
A: Yes, a lot of people have friends in different regions and we want to allow them to easily interact. One of the things that makes DotA special is how big the community is, so we will do our best to make it easy to connect and communicate with one another.


Q: How are you going to handle delay and lag between players? (by Alex)
A: This is something we are putting a lot of time and resources into. Minimizing delay to servers, along with optimizing networking code, is very important to being able to enjoy DotA on both a casual and competitive level. We’re expanding the Steam infrastructure around the world so the matchmaking service for DotA 2 is able to provide the lowest possible ping wherever you are playing. There will also be some uniquely located servers that are optimized regionally for handling longer distance matches.

Source : Dota2 - gosugamers